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NeoReviews Vol.8 No.3 2007 e127
© 2007 American Academy of Pediatrics
* Division of Genetics, Department of Pediatrics, Tufts-New England Medical Center, Boston, Mass
Assisted reproductive technology (ART) techniques have enabled couples with low fertility to conceive, and approximately 1% of births in the United States result from such procedures. ART combined with preimplantation genetic diagnosis (PGD) has provided a method for couples at risk for genetic conditions to deliver a baby free from the condition. ART presents many perinatal risks and may be associated with long-term health effects for the offspring. PGD, which can screen for known conditions, at present cannot screen for all genetic conditions.
Abbreviations: ART: assisted reproductive technology CDC: Centers for Disease Control and Prevention FISH: fluorescent in situ hybridization HIV: human immunodeficiency virus ICSI: intracytoplasmic sperm injection IVF: in vitro fertilization PCR: polymerase chain reaction PGD: preimplantation genetic diagnosis
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